Bristol Dementia Research Grouping - Network Coordinator, Prof Gordon Wilcock
The Bristol Dementia Research Group was established in 1984 and has a research programme that spans the spectrum from the patient at one end to the gene in the laboratory at the other end. We have a multidisciplinary approach, the research team including experts in neuropathology, clinically related genetic technology, molecular genetics, neuropsychology, psychiatry, ad other clinically releveant disciplines. We also have collaborative venutures with colleagues elsewhere in the UK and abroad. Membership of the ART Network will facilitate our ability to collaborate with colleagues elsewhere, and the recent award of an ART grant of £50,000 for the purchase of imaging equipment will significantly strengthen our work investigating the structural changes in the brains of people with dementia. (Prof Gordon Wilcock)
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Nottingham Group for the Study of Neurodegenerative Disorders, University of Nottinghaming - Network Coordinator, Dr Kevin Morgan
The University of Nottingham has had a research interest in neurodegenerative disorders since 1986. The group is comprised of three units, which brings together expertise in the fields of protein chemistry, neuropathology and molecular genetics. In recent years, in collaboration with other national neuroscience units, we have established an anonymised DNA bank which currently holds over 500 samples from various neurodegenerative disease groups (predominantly Alzheimer's disease) together with age-matched controls. There is an active programme of donation of brain tissue to a brain bank with consent of family members together with an active patient support group (Neuroscience Support Group at Queen’s Medical Centre), which runs a biannual research and care all day symposium. As a result of being a member of the ART Network the DNA bank should grow and collaborative studies with other Network members will maximum the benefit of this collection.
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Oxford Project to Investigate Memory and Ageing - Network Co-ordinator, Prof David Smith
OPTIMA has been running for nearly twelve years. The project compares the brain in normal ageing with changes in the brain that occur in dementia and is based on the philosophy that research into dementia can be facilitated by a caring environment. Participants in the centre cover a wide range of disciplines, including psychiatry of old age, nursing, neuropathology, radiology, epidemiology, experimental psychology, molecular biology and genetics. "We are keen to participate in the Network since it will facilitate the exchange of ideas which is a powerful stimulus to new research" (Prof David Smith)
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Newcastle Dementia Research Group - Network Co-ordinator, Prof I G McKeith
Since 1979, the Newcastle Dementia Research Group has focussed upon brain ageing and dementia, helping to establish AD as the major cause of dementia in old age. Recent work has investigated other important disorders such as dementia with Lewy Bodies. "The Institute for the Health of the Elderly shares the Alzheimer's Research Trust's vision of collaboration between research centres" (Prof E G McKeith)
University of Manchester, AD Research Group - Network Co-ordinator, Prof David Mann
"Manchester has a unique range of expertise in AD and other dementias ranging from clinical perspectives to molecular biology. This type of support will serve as a catalyst for further collaborative work involving the Manchester group" (Prof David Mann)
The Neurosciences Institute, Dundee - Network Co-ordinator, Dr Kieran Breen
"The Neurosciences Institute at Dundee has been carrying out research for over 6 years to study the biochemical mechanism underlying the disease to identify early markers which may serve as potential therapeutic targets to prevent the disease progression. The establishment of an AD research centre will greatly aid in the integration of the diverse strands of clinical and non-clinical research" (Dr Kieran Breen)
University of Wales College of Medicine (Cardiff) - Network Co-ordinator, Prof Michael Owen
"We in the Neuropsychiatric Genetics Unit at the University of Wales College of Medicine have been working on the genetics of Alzheimer's disease for the last 7 years. We hope that identification of the genes responsible will eventually lead to more effective treatments for this terrible disorder" (Prof Mike Owen)
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University of Cambridge Addenbrook's Hospital - Network Co-ordinator, Prof John Hodges
"The University has a long-standing commitment to Alzheimer's research and has many world class investigators" (Prof Sir Keith Peters). The groups comprising Prof Hodges' centre have interests in characterisation of AD in its early stages, imaging techniques, neuro psychiatry and psychology, clinical genetics, epidemiological studies of AD and its basic biology.
University of Aberdeen - Network Co-ordinator, Prof. Claude Wischik
"Aberdeen's interest is to establish a multi-disciplinary centre to develop and test a treatment aiming to prevent the neurofibrillary degeneration discovered by Alzheimer. This will bring tangible benefits to patients and help open up the paradigms…of treatment approaches to the disease" (Prof. Claude Wischik)
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Alzheimer's
Research Trust Network Members
We
are pleased to acknowledge the kind help of Lloyd's Charities Trust, on behalf
of Lloyd's insurance
market, and other generous donors in funding this network
Dementia Research Group, Institute of Neurology, London - Network Co-ordinator, Prof Martin Rossor
"The grant will provide urgently needed support for the administrative infrastructure of our rapidly developing research group..our full productivity and ability to collaborate externally (has been) handicapped by lack of administrative support" (Prof Martin Rossor)
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Neurodegeneration Interdisciplinary Research Group, Institute of Psychiatry, London - Network Coordinator, Prof Simon Lovestone
Alzheimer’s disease and related dementia has long been a focus for research activity at the Institute of Psychiatry. The Neurodegeneration Interdisciplinary Research Group bring together molecular biology, genetics, clinical studies, neuroimaging, neuropathology, psychology and epidemiology with groups in each of these fields as internationally competitive. Some members of the NIRG compose the MRC cooperative group in Neurodegeneration and all members of the group have contributed to the five star status of the IOP. As a group we are delighted now to be members of the ART Network. Science of the present, and even more of the future, can only be achieved by groups working together. Good collaboration equals good science.
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We are pleased to acknowledge the kind help of Lloyd’s Charities Trust, on behalf of Lloyd’s insurance market, and other generous donors in funding this Network.
The Alzheimer’s Research Trust Network is designed to facilitate and encourage communication and collaboration between dementia researchers of different scientific disciplines all over the UK. The Network grant for each centre is £12,000 per year to cover the salary of a part-time Network administrator, their office costs and the Network annual conference. An additional £5,000 is given to fund direct research costs such as minor equipment, attendance at conferences, public meetings, etc.
University of Cambridge Addenbrooke’s
Hospital
Research in Cambridge into Alzheimer's and other forms of dementia is wide-ranging and multi-disciplinary. The ART Network brings together behavioural neurology, clinical psychiatry, neuropsychology, neuroimaging, clinical epidemiology, neuropathology, molecular pathology and experimental animal models of dementia. This group is extremely active, published 200 articles in peer reviewed scientific journals in the last three years. The award of the Network grant has allowed researchers from diverse disciplines to meet and has fostered inter-disciplinary research projects.
‘The Neurosciences Institute at Dundee has been carrying out Alzheimer research for over 8 years and encompasses a unique interdisciplinary grouping of basic scientists, clinicians and social scientists. The establishment of the AD research centre has greatly aided in the integration of these diverse strands of Alzheimer research in order to gain a greater understanding of the disease both at a biochemical and behavioural level.’(Dr Kieran Breen)
Dementia Research Group, Institute of Neurology, London
Network Coordinator, Prof Martin Rossor
The Queen Square group has focussed on early onset and familial dementias with multidisciplinary studies of the molecular genetics, neuroimaging, neuropsychology and treatment of this group of diseases. ‘These have provided important insights into the disease mechanisms and potential treatment but many of the disorders we study are rare; the ART network has facilitated our research.’ (Prof Martin Rossor)
‘Manchester has a unique range of expertise in AD and other dementias ranging from clinical perspectives to molecular biology. We are particularly interested in finding out how genetic risk factors influence the formation and accumulation of the pathological changes of the disease. [This] type of support serves as a catalyst for further collaborative work involving the Manchester group and other Network Centres.’ (Prof David Mann)
Newcastle Dementia Research Group
Network Coordinator, Prof Ian McKeith
Since 1979, the Newcastle Dementia Research Group has focused upon brain ageing and dementia, helping to establish AD as the major cause of dementia in old age. Recent work has investigated other important disorders such as dementia with Lewy Bodies and cerebrovascular disease. ‘The Institute for the Health of the Elderly shares the Alzheimer's Research Trust’s vision of collaboration between research centres. We greatly appreciate and are already benefiting from our membership of the ART network. We have succeeded in obtaining ART funding for a studentship and a project grant, both of which will complement our other ongoing research’. (Prof Ian McKeith)
Oxford Project to Investigate Memory and
Ageing
Network Coordinator, Prof David Smith
| Bristol Dementia Research Group Network Coordinator, Prof Gordon Wilcock The Bristol Dementia Research Group was established in 1984 and has a research programme that spans the spectrum from the patient at one end to the gene in the laboratory at the other end. We have a multidisciplinary approach, the research team including experts in neuropathology, clinically related genetic technology, molecular genetics, neuropsychology, psychiatry, ad other clinically releveant disciplines. We also have collaborative venutures with colleagues elsewhere in the UK and abroad. Membership of the ART Network will facilitate our ability to collaborate with colleagues elsewhere, and the recent award of an ART grant of £50,000 for the purchase of imaging equipment will significantly strengthen our work investigating the structural changes in the brains of people with dementia. (Prof Gordon Wilcock) |
| Neurodegeneration Interdisciplinary Research Group, Institute of Psychiatry, London Network Coordinator, Prof Simon Lovestone Alzheimer’s disease and related dementia has long been a focus for research activity at the Institute of Psychiatry. The Neurodegeneration Interdisciplinary Research Group bring together molecular biology, genetics, clinical studies, neuroimaging, neuropathology, psychology and epidemiology with groups in each of these fields as internationally competitive. Some members of the NIRG compose the MRC cooperative group in Neurodegeneration and all members of the group have contributed to the five star status of the IOP. As a group we are delighted now to be members of the ART Network. Science of the present, and even more of the future, can only be achieved by groups working together. Good collaboration equals good science. |
| Nottingham Group for the Study of Neurodegenerative Disorders,
University of Nottingham
Network Coordinator, Dr Kevin Morgan The University of Nottingham has had a research interest in neurodegenerative disorders since 1986. The group is comprised of three units, which brings together expertise in the fields of protein chemistry, neuropathology and molecular genetics. In recent years, in collaboration with other national neuroscience units, we have established an anonymised DNA bank which currently holds over 500 samples from various neurodegenerative disease groups (predominantly Alzheimer's disease) together with age-matched controls. There is an active programme of donation of brain tissue to a brain bank with consent of family members together with an active patient support group (Neuroscience Support Group at Queen’s Medical Centre), which runs a biannual research and care all day symposium. As a result of being a member of the ART Network the DNA bank should grow and collaborative studies with other Network members will maximum the benefit of this collection. |